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Product Datasheet
SizePriceCatalog #
5 ug99.00APT001-113-005Place Order
50 ug300.00APT001-113-050Place Order
1 mg3,500.00APT001-113-mgPlace Order
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Product NamehGH
DescriptionRecombinant protein of active form without-tag.
Molecular Mass22260.29 Daltons
SourceE.coli
Sizes5ug, 50ug, 1000ug
Purity>98%
Endotoxin LevelLess than 0.1 ng/ug (IEU/ug) of protein as determined by the LAL method.
FormulationRecombinant protein stored in 1 X PBS, 10% glycerol.
Storage and StabilityStored at below -20C. It is stable at 4C between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Purification SystemPurified by chromatographic techniques at least two methods.
Purity Purification
Country of OriginCANADA
UsageCell culture
BackgroundHuman growth hormone: hGH is a peptide hormone that belongs to a group of homologous hormones which function as growth promoters and induces lactogenic activity. hGH activates MAPK/ERK pathway in chondrocyte cells which stimulates the multiplication and division of chondrocytes in cartilage tissue (1). hGH stimulates the JAK-STAT pathway in liver and target cells to produce IGF-1 that functions to promote osteoblast and chondrocyte activity for bone growth (1). hGH also functions to stimulate muscle growth, lipolysis, gluconeogenesis (2), protein synthesis and the immune system.
References1. Binder G, Wittekindt N, Ranke MB (February 2007). "Noonan Syndrome: Genetics and Responsiveness to Growth Hormone Therapy". Horm Res 67 (Supplement 1): 45C49 2. King, MW (2006). "Structure and Function of Hormones: Growth Hormone". Indiana State University. Retrieved 2008-01-16


 
 

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