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Product Datasheet
SizePriceCatalog #
5 ug99.00APT001-035-005Place Order
50 ug300.00APT001-035-050Place Order
1 mg3,500.00APT001-035-mgPlace Order
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Product NameTrail
DescriptionRecombinant protein of active form without-tag.
Molecular Mass19523.91 Daltons
SourceE.coli
Sizes5ug, 50ug, 1000ug
Purity>98%
Endotoxin LevelLess than 0.1 ng/ug (IEU/ug) of protein as determined by the LAL method.
FormulationRecombinant protein stored in 1 X PBS, 10% glycerol.
Storage and StabilityStored at below -20C. It is stable at 4C between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Purification SystemPurified by chromatographic techniques at least two methods.
Purity Purification
Country of OriginCANADA
UsageCell culture
BackgroundTNF-related apoptosis inducing ligand: Trail or TNF-related apoptosis inducing ligand is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family which function as prominent mediators of immune regulation and the inflammatory response. TRAIL induces significant cell death in human colon polyps and providing a potentially selective approach for colorectal cancer chemoprevention by targeting APC-deficient cells for apoptosis (1). TRAIL plays a crucial role in hepatic cell death and hepatic inflammation (2).
References1. Zhang, L. et.al: Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. Nature 464: 1058-1061, 2010. 2. Zheng, S.-J. et.al: Critical roles of TRAIL in hepatic cell death and hepatic inflammation. J. Clin. Invest. 113: 58-64, 2004.


 
 

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