Advanced Protein Technology Company Brochure  
   

 
Product Datasheet
SizePriceCatalog #
5 ug99.00APT001-039-005Place Order
50 ug300.00APT001-039-050Place Order
1 mg3,500.00APT001-039-mgPlace Order
 Download Datasheet in PDF
Product NameTGF-b3
DescriptionRecombinant protein of active form without-tag.
Molecular Mass12852.77 Daltons
SourceE.coli
Sizes5ug, 50ug, 1000ug
Purity>98%
Endotoxin LevelLess than 0.1 ng/ug (IEU/ug) of protein as determined by the LAL method.
FormulationRecombinant protein stored in 1 X PBS, 10% glycerol.
Storage and StabilityStored at below -20C. It is stable at 4C between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Purification SystemPurified by chromatographic techniques at least two methods.
Purity Purification
Country of OriginCANADA
UsageCell culture
BackgroundTGF-3 or transforming growth factor, beta 3 is a member of the TGF family of proteins that is a ser/thr protein kinase. TGFB3 is involved in embryogenesis and cell differentiation. TGFB3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development (1). TGFB3 function in normal palate and lung morphogenesis and implicates this cytokine in epithelial-mesenchymal interaction (2).
References1. Nawshad, A. et.al: TGF-beta-3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development. J. Cell Biol. 163: 1291-1301, 2003. 2. Kaartinen, V. et.al: Abnormal lung development and cleft palate in mice lacking TGF-beta-3 indicates defects of epithelial-mesenchymal interaction. Nature Genet. 11: 415-421, 1995.


 
 

  • Refolding Services
  • rScAb Production
  • Periplasmic Protein Expression
  • Custom Cleavaged Protein

Contact us | About us | Log In | Place Order | Terms & Privacy
©2016 - Advanced Protein Technology