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Product Datasheet
SizePriceCatalog #
5 ug99.00APT001-070-005Place Order
50 ug300.00APT001-070-050Place Order
1 mg3,500.00APT001-070-mgPlace Order
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Product NamePOU5
DescriptionRecombinant protein of active form without-tag.
Molecular Mass21257.30 Daltons
SourceE.coli
Sizes5ug, 50ug, 1000ug
Purity>98%
Endotoxin LevelLess than 0.1 ng/ug (IEU/ug) of protein as determined by the LAL method.
FormulationRecombinant protein stored in 1 X PBS, 10% glycerol.
Storage and StabilityStored at below -20C. It is stable at 4C between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Purification SystemPurified by chromatographic techniques at least two methods.
Purity Purification
Country of OriginCANADA
UsageCell culture
BackgroundOctamer-binding transcription factor 4/ POU domain class 5 transcription factor 1: OCT-4/POU5 is a growth factor belonging to the POU family which functions in regulating stem cell differentiation. OCT-4 is involved in the promotion of undifferentiated embryonic stem cell self-renewal (1). OCT-4 can also induce tumorigenesis through inhibition of cellular diffeentiation in adult germ cells (2).
References1. Zaehres H, Lensch MW, Daheron L, Stewart SA, Itskovitz-Eldor J, Daley GQ. 2005. "High-efficiency RNA interference in human embryonic stem cells". Stem Cells 23 (3): 299C305. 2. Hochedlinger K, Yamada Y, Beard C, Jaenisch R. 2005. "Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues". Cell 121(3): 465C77


 
 

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