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Product Datasheet
SizePriceCatalog #
5 ug30.00APT001-106-005Place Order
50 ug50.00APT001-106-050Place Order
1 mg700.00APT001-106-mgPlace Order
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Product NameLeptin
DescriptionRecombinant protein of active form without-tag.
Molecular Mass16157.67 Daltons
SourceE.coli
Sizes5ug, 50ug, 1000ug
Purity>98%
Endotoxin LevelLess than 0.1 ng/ug (IEU/ug) of protein as determined by the LAL method.
FormulationRecombinant protein stored in 1 X PBS, 10% glycerol.
Storage and StabilityStored at below -20C. It is stable at 4C between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Purification SystemPurified by chromatographic techniques at least two methods.
Purity Purification
Country of OriginCANADA
UsageCell culture
BackgroundLeptin is a serum protein produced by adipocytes that play a main role in the regulation of body fat. Leptin is a growth factor in colonic epithelial cells and one that may provide a biological explanation for the observed associations between obesity, physical activity, and colon cancer (1). Leptin appears to be able to control the proliferation of both normal and malignant breast epithelial cells and used for normal mammary gland development (2).
References1. Hardwick JC. Et.al : Leptin is a growth factor for colonic epithelial cells. Gastroenterology. 2001 Jul;121(1):79-90. 2. X Hu. Et.al: Leptin--a growth factor in normal and malignant breast cells and for normal mammary gland development. J Natl Cancer Inst. 2002 Nov 20;94(22):1704-11.


 
 

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