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Product Datasheet
SizePriceCatalog #
5 ug99.00APT001-057-005Place Order
50 ug300.00APT001-057-050Place Order
1 mg3,500.00APT001-057-mgPlace Order
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Product NameIP-10
DescriptionRecombinant protein of active form without-tag.
Molecular Mass8776.49 Daltons
SourceE.coli
Sizes5ug, 50ug, 1000ug
Purity>98%
Endotoxin LevelLess than 0.1 ng/ug (IEU/ug) of protein as determined by the LAL method.Less than 0.1 ng/ug (IEU/ug) of protein as determined by the LAL method.
FormulationRecombinant protein stored in 1 X PBS, 10% glycerol.
Storage and StabilityStored at below -20C. It is stable at 4C between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Purification SystemPurified by chromatographic techniques at least two methods.
Purity Purification
Country of OriginCANADA
UsageCell culture
BackgroundIP-10 or interferon gamma inducible protein 10 is a member of the CXC chemokine family that plays a role in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. IP10 participate in the regulation of angiogenesis during inflammation and tumorigenesis (1). IP10 plays a role in the generation and delivery of an effector T-cell response (2).
References1. Angiolillo, A. L. et.al: Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J. Exp. Med. 182: 155-162, 1995. 2. Dufour, J. H. et.al: IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J. Immun. 168: 3195-3204, 2002.


 
 

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