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Product Datasheet
SizePriceCatalog #
5 ug99.00APT001-054-005Place Order
50 ug300.00APT001-054-050Place Order
1 mg3,500.00APT001-054-mgPlace Order
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Product NameIL-8
DescriptionHuman active form IL-8 , tag-free form.
Molecular Mass7987.36 Daltons
SourceE.coli
Sizes5ug, 50ug, 1000ug
Purity>98%
Endotoxin LevelLess than 0.1 ng/ug (IEU/ug) of protein as determined by the LAL method.
FormulationRecombinant protein stored in 1 X PBS, 10% glycerol.
Storage and StabilityStored at below -20C. It is stable at 4C between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Purification SystemPurified by chromatographic techniques at least two methods.
Purity Purification
Country of OriginCANADA
UsageCell culture
BackgroundIL-8 or interleukin 8 is a member of the CXC chemokine family that is one of the major mediators of the inflammatory response and several cell types secrete this chemokine. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 plays an essential role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection (1). IL8 is produced and released from human adipose tissue and from isolated adipocytes in vitro, which may indicate that IL8 from adipose tissue could be involved in some obesity-related complications (2).
References1. Smyth, R. L. et.al: The association between disease severity, cytokines and virus genotype in infants with respiratory syncytial virus (RSV) bronchiolitis. Arch Dis. Child. 82 (Suppl. 1): A4-A5, 2000. 2. Bruun, J. M. et.al : Regulation of interleukin 8 production and gene expression in human adipose tissue in vitro. J. Clin. Endocr. Metab. 86: 1267-1273, 2001.


 
 

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