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Product Datasheet
SizePriceCatalog #
5 ug99.00APT001-034-005Place Order
50 ug300.00APT001-034-050Place Order
1 mg3,500.00APT001-034-mgPlace Order
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Product NameBMP 2
DescriptionRecombinant protein of active form without-tag.
Molecular Mass13035.06 Daltons
SourceE.coli
Sizes5ug, 50ug, 1000ug
Purity>98%
Endotoxin LevelLess than 0.1 ng/ug (IEU/ug) of protein as determined by the LAL method.
FormulationRecombinant protein stored in 1 X PBS, 10% glycerol.
Storage and StabilityStored at below -20C. It is stable at 4C between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Purification SystemPurified by chromatographic techniques at least two methods.
Purity Purification
Country of OriginCANADA
UsageCell culture
BackgroundBMP-2 is a member of the bone morphogenetic protein family that is part of the transforming growth factor-beta (TGFB) superfamily. BMP-2 acts as a disulfide-linked homodimer that induces bone and cartilage formation. BMP2 modulates fibroblast-like synoviocyte cell populations in inflamed synovium (1). BMP2 plays a role in human T-cell differentiation and involve in the long bone formation (2).
References1. Lories, R. J. U. et.al: Bone morphogenetic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis. Arthritis Rheum. 48: 2807-2818, 2003. 2. Cejalvo, T. et.al: Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development. Immunology 121: 94-104, 2007.


 
 

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